Pathophysiology of Migraine: A Disorder of Sensory Processing

Pathophysiology of Migraine: A Disorder of Sensory Processing.

Plaguing humans for more than two millennia, manifest on every continent studied, and with more than one billion patients having an attack in any year, migraine stands as the sixth most common cause of disability on the planet. The pathophysiology of migraine has emerged from a historical consideration of the "humors" through mid-20th century distraction of the now defunct Vascular Theory to a ...

Audiovestibular Sensory Processing in Migraine

Pathophysiology of migraine.

The cause and pathophysiology of migraine are not well understood. Over the years research into migraine pathophysiology has focused on the physiology and pharmacology of the headache, the changes in cerebral cortex associated with the symptoms of the aura, and more recently the genetics underlying the migraine syndromes. In this discussion, the neuroanatomical structures activated during migra...

Migraine – Pathophysiology of Pain

Migraine is a primary episodic headache disorder characterized by a cascade of events that involve various combinations of neurologic, gastrointestinal and autonomic changes. Headache is probably caused by activation of meningeal and blood vessel nociceptors combined with an alteration in central pain modulation. Headache and its associated neuro-vascular changes are subserved by the trigeminal...

[Pathophysiology of migraine chronification].

In approximately 3％ of migraineurs, migraine evolves into more protracted and severe conditions annually. Meanwhile, approximately 26％ of chronic migraine cases regain the episodic nature of migraine headaches in two years. The prevalence of chronic migraine is estimated to be approximately 1％. Although the pathophysiology of migraine chronification is poorly understood, several studies have de...